 | Dr. Sasha ZakhartchoukViral Pathogenesis & Vaccine Development
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Biography
Sasha has a M.Sc. in Biochemistry and a Doctorate in Veterinary Medicine from the Moscow Veterinary Academy. Following this, he completed his PhD at the Research Institute of Agricultural Biotechnology in Moscow in 1995. Since joining VIDO, Sasha has been working on molecular characterization of non-human adenoviruses to develop them as live vaccine vectors for animals and humans. In addition, Sasha was involved in developing a vaccine against SARS. He holds two patents and has published 30 peer-reviewed manuscripts, 1 book chapter.
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Responsibilities: ♦ Manager: PRRSV vaccine project ♦ Manager: Measles vaccine project Education: Moscow Veterinary Academy by K.I. Skryabin, 1991, MSc in Biochemistry and DVM Relevant work experience: |
Expertise: Major accomplishments:
Development of non-human adenoviruses as gene delivery vectors. Intranasal immunization of calves with recombinant bovine adenovirus-3 expressing a bovine herpesvirus-1 antigen partially protected calves from clinical disease and reduced the time of herpesvirus shedding. A member of a team of the Canadian scientists who worked on development of a vaccine for SARS coronavirus. As a result of this work, four different SARS vaccine candidates were tested for their immunogenicity in mice, and two of them were evaluated for ability to protect against live SARS coronavirus challenge in murine and ferret model of infection.
CURRENT RESERCH AREAS Virus-host cells interactions
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