VIDO-InterVac

Vaccine and Infectious Disease Organization -
International Vaccine Centre

Prevention of colonization of poultry with C. jejuni by vaccination

Project Leaders: Brenda Allan, Wolfgang Koester, Andrew Potter

Campylobacteriosis, caused by the bacteria Campylobacter jejuni, is one of the most reported food borne gastro-enteric diseases in humans.Although C. jejuni colonization causes no harmful effects to the bird, the handling, preparation and consumption of contaminated poultry is considered to be the main source of infection in humans.

C. jejuni contamination at retail remains high despite farm biosecurity and processing control measures.In an effort to improve food safety our research has targeted the development of an in ovo vaccine to prevent colonization in poultry. Current efforts are focused on selecting subunit proteins and investigating adjuvant effectiveness.

Objectives:

  • Investigate adjuvants best suited for in ovo use
  • Development of a subunit vaccine delivered in ovo for the prevention of colonization of poultry by C. jejuni