Prevention of colonization of poultry with C. jejuni by vaccination
Campylobacteriosis, caused by the bacteria Campylobacter jejuni, is one of the most reported food borne gastro-enteric diseases in humans. Although C. jejuni colonization causes no harmful effects to the bird, the handling, preparation, and consumption of contaminated poultry is the main source of infection in humans.
C. jejuni contamination at retail is high despite farm biosecurity and processing control measures. To improve food safety our research targets the development of an in ovo poultry vaccine to prevent colonization. Current efforts focus on selecting subunit proteins and investigating adjuvant effectiveness.