Vaccine Formulation & Delivery
The Vaccine Formulation and Delivery research group aims to improve vaccines by developing new formulations and delivery mechanisms. Research focuses on the discovery and development of new adjuvants, the development of vaccines for specialized populations (e.g. neonates and the elderly), and understanding vaccine retention and distribution in the body. New delivery methods are also being investigated including the use of viral and bacterial vectors, mucosal delivery, and the development of needle-free and topical vaccines.
Prion diseases:
Mucosal immunity:
- Assess regional and kinetic changes in gut permeability and the mechanisms of transport across the piglet gut wall
- Intrauterine immunization – a novel approach to induce broad mucosal immunity
- Induction and regulation of mucosal immunity in the neonate
Immune modulation:
Viral vaccine vectors:
- Adenovirus vectors for vaccine delivery
Technology platforms:
- Development and application of peptide arrays for kinome analysis in agricultural species
- Comparative immunology – innate immunity in bees
- Development of novel vaccine for newborns against Lawsonia intracellularis (Ileitis)