VIDO-InterVac

Vaccine and Infectious Disease Organization -
International Vaccine Centre

Innate immune stimulators as alternatives to antibiotics and adjuvants for poultry vaccines

Project Team: Arshud Dar, Brenda Allan, Wolfgang Koester, Colette Wheler

Yolk sac infection (YSI) is the most common reason for early chick mortality. The disease is caused by a wide range of bacteria including coliform bacteria, Staphylococcus, Streptococcus, Proteus, and Salmonella. YSI is managed by on-farm practices, heavy culling at the farm level, and the administration of antibiotics. Concerns with antibiotic use has led to a need for an alternative approach.

We will characterize a repertoire of innate immune stimulants capable of serving as alternatives to antibiotics for control of bacterial infections and strengthening of immunity in young chicks.