Yolk sac infection (YSI) is the most common reason for early chick mortality. The disease is caused by a wide range of bacteria including coliform bacteria, Staphylococcus, Streptococcus, Proteus, and Salmonella. YSI is managed by on-farm practices, heavy culling at the farm level, and the administration of antibiotics. Concerns with antibiotic use has led to a need for an alternative approach.
We will characterize a repertoire of innate immune stimulants capable of serving as alternatives to antibiotics for control of bacterial infections and strengthening of immunity in young chicks.